Abdominal Aortic Aneurysm Repair with Ancure Endograft

Abdominal Aortic Aneurysms are a significant and relatively common vascular problem. The incidence of aneurysms will dramatically increase as the population ages. 1.5 million Americans have an abdominal aortic aneurysm with 200,000 new cases diagnosed each year. The remaining patients are followed expectantly. The prevalence among males 65-74 years old is 3-6% and may be as high as 12% in males with hypertension.

Diagnosis and treatment of this disease is very important. Ruptured abdominal aortic aneurysms result in 15,000 deaths per year in the U.S. (13th leading cause of death in U.S.) Emergency repair has high perioperative mortality (40-50%) as compared to elective repair (1-5%).

Open surgical repair is the standard treatment for Abdominal Aortic Aneurysm; however, endografts and endovascular stent grafts have recently been developed and allow less invasive treatment of some aneurysms. Open repair requires a large abdominal incision as well as clamping of the aorta above and below the aneurysm. The aorta is then opened and a graft is sewn in. There is also extensive bowel manipulation involved. This surgery has an 18% complication rate with prolonged hospitalization and associated morbidity. Virtually all patients require an NG tube secondary to ileus from bowel manipulation. Moreover, patients also spend a significant length of time in the intensive care unit.

In contrast, placement of an endograft avoids an open abdominal incision with only bilateral groin cut-downs necessary. Moreover, there is no bowel manipulation and overall complications are cut in half. This translates into decreased hospital stay (9.3 days for open repair vs. 3.4 days for endograft) and faster time to ambulation (3.6 days for open repair vs. 1.4 for endograft).

Unfortunately, only 15-30% of aneurysm patients are candidates for endograft placement. Anatomic limitations for endograft placement include aneurysms that involve the renal arteries, aneurysms with extremely short necks, iliac vessels that are less than 7 mm or greater than 13.4 mm in diameter, densely calcified vessels, very small femoral vessels, and severe angulation of the aneurysm neck. These limitations make preoperative measurement and evaluation of the aneurysm very important; consequently, both conventional angiography and CT angiography need to be performed. These imaging procedures can be performed on an out-patient basis.

In summary, endograft placement allows 15-30% of abdominal aortic aneurysms to be treated by less invasive means with a decrease in morbidity when compared to open surgical repair.

This procedure is performed by SDI Radiologists at St. Joseph's Hospital.


References:
Murphy, KD, Richter, GM, Henry, M, Encarnacion, CE, Le, VA, & Palmaz, JC. 1996. Aortoiliac aneurysms: management with endovascular stent-graft placement. Radiology, 198: 473-480.

Dorffner, R, Thurnher, S, Polterauer, P, Kretschmer, G, & Lammer, J. 1997. Treatment of abdominal aortic aneurysms with transfemoral placement of stent-grafts: complications and secondary radiologic intervention. Radiology. 204: 79-86.

Costello, P. & Gaa, J. 1995. Spiral CT angiography of abdominal aortic aneurysms. RadioGraphics, 15: 397-406.

Duda, SH, Raygrotzki, S, Wiskirchen, J, Khalighi, K, Schott, U, Bares, R, Ziemer, G, & Claussen, CD. 1998. Abdominal aortic aneurysms: treatment with juxtarenal placement of covered stent-grafts. Radiology, 206: 195-198.

Moritz, JD, Rotermund, S, Keaeting, DP, & Oestmann, JW. 1996. Infrarenal abdominal aortic aneurysms: implications of CT evaluation of size and configuration for placement of endovascular aortic grafts. Radiology, 198: 463-466.

Chuter, TAM, Gordon, RL, Reilly, LM, Kerlan, RK, Sawhney, R, Jean-Claude, J, Canto, CJ, LaBerge, JM, Ring, EJ, Wall, SD, & Messina, LM. 1999. Abdominal Aortic Aneurysm in High-Risk Patients: Short- to Intermediate-term Results of Endovascular Repair. Radiology, 210: 361-365.

Orton, DF, LeVeen, RF, Saigh, JA, Culp, WC, Fidler, JL, Lynch, TJ, Goertzen, TC, & McCowan, TC. 2000. Aortic Prosthetic Graft Infections: Radiologic Manifestations and Implications for Management. Radiographics, 20: 977-993.

Blum, U, Langer, M, Spillner, G, Mialhe, C, Beyersdorf, F, Buitrago-Tellez, C, Voshage, G, Duber, C, Schlosser, V, & Cragg, AH. 1996. Abdominal aortic aneurysms: preliminary technical and clinical results with transfemoral placement of endovascular self-expanding stent-grafts. Radiology, 198: 25-31.

Braunwald, E, et al, (editors). Harrison's Principles of Internal Medicine, 11th Edition. 1987. New York:McGraw-Hill. pp. 1037-1039.

 

 

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